N,N-Bis[(1S)-(-)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine - Names and Identifiers
Name | N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine
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Synonyms | N N-BIS-[(S)-1-PHENYLETHYL]DIBENZO[D F][ Biphenyl-2,2'-diyl bis((1S)-1-phenylethyl)phosphoramidite 1,1'-Biphenyl-2,2'-diyl bis((1S)-1-phenylethyl)phosphoramidite N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine N,N-bis[(1R)-1-phenylethyl]-Dibenzo[d,f][1,3,2]dioxaphosphepin-6-aMine N,N-Bis[(1R)-(+)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine N,N-Bis[(1S)-(-)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine Dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine, N,N-bis[(1S)-1-phenylethyl]- BIPOL-A1(S), (S,S)-N-(5,7-Diox-6-phosphadibenzo[a,c]cyclohepten-6-yl)bis(1-phenylethyl)amine, O,Oμ-(2,2μ-Biphenyldiyl) N,N-bis[(S)-1-phenylethyl]phosphoramidite
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CAS | 376355-58-7
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N,N-Bis[(1S)-(-)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine - Physico-chemical Properties
Molecular Formula | C28H26NO2P
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Molar Mass | 439.492 |
Melting Point | 99-102 °C |
Boling Point | 578.4±53.0 °C(Predicted) |
Appearance | Powder |
Color | white |
pKa | -0.31±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | moisture sensitive |
N,N-Bis[(1S)-(-)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine - Risk and Safety
N,N-Bis[(1S)-(-)-phenylethyl]dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine - Introduction
N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine is an organic compound. Its main properties are as follows:
-Appearance: White crystalline solid
-Molecular formula: C32H27NOPO2
-Molecular weight: 507.55g/mol
This compound is often used as a catalyst, ligand or intermediate for catalytic reactions in organic synthesis. Some specific uses include:
1. Asymmetric catalyst: as an auxiliary ligand of metal catalyst, it participates in asymmetric catalytic reactions, such as the synthesis of asymmetric imidazolones.
2. Chiral inducers in asymmetric catalytic reactions: by forming complexes with metal catalysts, Chiral Induction is realized and the stereoselectivity of the reaction is improved.
3. Optical materials: Due to its symmetrical molecular structure, it can be used as a raw material for preparing optical materials.
Regarding the preparation method, the synthesis method of N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine may include the following steps:
1. Reacting phenethyl lithium with dibenzoquinone to generate dibenzol.
2. Reacting dibenzo alcohol with sulfoxide to generate dibenzo ether.
3. Reacting dibenzo ether with phosphorus oxychloride to generate N,N-dibenzo-acyl dibenzo ether.
4. React N,N-dibenzoyl dibenzo ether with hydrogen amino group to generate N,N-bis ((S)-1-phenylethyl) dibenzo ether. This is then suitably treated to give N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine.
The following safety information should be noted when using N,N-Bis((S)-1-phenylethyl)dibenzo[d,f][1,3,2]dioxaphosphepin-6-amine:
-This compound may be irritating, please avoid contact with skin, eyes and respiratory tract. Appropriate protective equipment, such as lab gloves, goggles and protective masks, is required for operation.
-During use or storage, please keep it away from oxidants and high temperature environments to avoid danger.
-Disposal should comply with relevant waste management regulations and should not be dumped or discharged into the environment.
Last Update:2024-04-10 22:29:15